Timi risk score stemi11/24/2023 ![]() ![]() ![]() 2 Specifically, the TIMI (Thrombolysis in Myocardial Infarction) for NSTEMI, 3 the TIMI for STEMI, 4 and the GRACE (Global. Left ventricular ejection fraction (LVEF) Mortality ST segment elevation myocardial infarction (STEMI) Thrombolysis in myocardial infarction (TIMI). Recent American Heart Association/American College of Cardiology guidelines recommend using risk scores to assess prognosis in people with nonSTsegment elevation myocardial infarction (NSTEMI) 1 and STsegment elevation myocardial infarction (STEMI). LVEF was associated with in-hospital and long-term mortality in STEMI patients and had additive prognostic value to TIMI risk score. The addition of LVEF to TIMI risk score enhanced net reclassification improvement (0.864 for in-hospital death, p < 0.001 0.510 for 1-year death, p < 0.001). Several scores have recently been proposed, derived either from clinical trials (eg, the Thrombolysis in Myocardial Infarction TIMI score, 1,2 the Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy trial PURSUIT score, 3 the Intravenous nPA Treatment of Infarcting Myocardium Early II InTIME II. When compared with the TIMI risk score alone, the addition of LVEF was associated with significant improvements in predicting in-hospital (AUC: 0.854 vs 0.803, p = 0.033) or 1-year death (AUC: 0.763 vs 0.728, p = 0.016). The TIMI risk score for STEMI predicts in-hospital mortality and adverse events in patients without cardiogenic shock undergoing primary angioplasty The TIMI risk score for STEMI prior to primary PCI can predict in hospital mortality and identifies a group of high-risk patients who might develop adverse events. LVEF had good predictive value for in-hospital death (AUC: 0.838 vs 0.803, p = 0.571) or 1-year death (AUC: 0.743 vs 0.728, p = 0.775), which was similar to TIMI risk score. Multivariate analysis showed that TIMI risk score (OR 1.24, 95 % CI 1.04-1.48, P = 0.015) and LVEF (OR 3.85, 95 % CI 1.58-10.43, P = 0.004) were independent predictors of in-hospital death. The rates of in-hospital death (0.5 vs 3.2 vs 10.3 %, p < 0.001) and major adverse cardiovascular events (14.6 vs 22.5 vs 40.6 %, p < 0.001) were significantly higher in high-risk group. Multivariate logistic regression was used to determine risk predictors. The predictive value was evaluated using the receiver operating characteristic. 673 patients with STEMI were divided into three groups based on TIMI risk score for STEMI: low-risk group (TIMI ≤3, n = 213), moderate-risk group (TIMI 4-6, n = 285), and high-risk group (TIMI ≥7, n = 175). To investigate whether the addition of left ventricular ejection fraction (LVEF) to the TIMI risk score enhances the prediction of in-hospital and long-term death in ST segment elevation myocardial infarction (STEMI) patients. ![]()
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